Andy Murray received a first-round bye before beating Gilles Muller in the second round on Wednesday

World number one Andy Murray suffered a shock third-round defeat in the Monte Carlo Masters, beaten by Spanish 15th seed Albert Ramos-Vinolas.

Murray, 29, fell to a 2-6 6-2 7-5 defeat in only his second Tour match after a month out with an elbow injury.

The Briton was in control of the decider after taking a 4-0 lead, but Ramos-Vinolas hit back with successive breaks to set up a famous victory.

Marin Cilic awaits Ramos-Vinolas in the last eight after beating Tomas Berdych.

Murray was playing his first tournament since being beaten in the second round at Indian Wells in March.

He beat Gilles Muller in straight sets in the second round on Wednesday, but admitted afterwards his elbow injury was still causing him some problems.

Murray began his match against Muller with three double faults in the first four points of the match, and his service game was again an issue against Ramos-Vinolas.

The Scot was broken seven times as 29-year-old Ramos-Vinolas claimed a first ever win against a world number one.

Murray showed trademark fight in fending off three break points at 4-4 in the decider, but could not respond when the Spaniard was in the ascendancy in his next service game.

Murray briefly threatened to break back with the score at 30-30 as Ramos-Vinolas served for the match, but he dragged a forehand wide and misjudged a drop shot into the net at match point.

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